Chaperonin GroEL (Cpn60) requires cofactor GroES (Cpn10) for protein refolding in bacteria that possess single groEL and groES genes in a bicistronic groESL operon. Among 4. 861 completely-sequenced prokaryotic genomes. 884 possess duplicate groEL genes and 770 possess groEL genes with no neighboring groES. https://www.getpureroutine.com/