Abstract Background mRNA expression data from next generation sequencing platforms is obtained in the form of counts per gene or exon. Counts have classically been assumed to follow a Poisson distribution in which the variance is equal to the mean. The Negative Binomial distribution which allows for over-dispersion. i. https://safeersappliancers.shop/product-category/bosch-kad93vbfpg-serie-6-american-side-by-side-fridge-freezer-with-ice/