Recently approved adeno-associated viral (AAV) vectors for liver monogenic diseases haemophilia A and B are exemplifying the success of liver-directed viral gene therapy. In parallel. additional gene therapy strategies are rapidly emerging to overcome some inherent AAV limitations. such as the non-persistence of the episomal transgene in the rapidly growing liver and immune response. https://lecoureures.shop/product-category/course-a-pied-femme-vetements-manteau/